Oxypurinol
Oxypurinol Uses, Dosage, Side Effects, Food Interaction and all others data.
Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Trade Name | Oxypurinol |
Generic | Oxypurinol |
Oxypurinol Other Names | Alloxanthine, DHPP, Ossipurinolo, Oxipurinol, Oxipurinolum, Oxoallopurinol, Oxypurinol |
Type | |
Formula | C5H4N4O2 |
Weight | Average: 152.1109 Monoisotopic: 152.033425392 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Intended for the treatment of congestive heart failure and hyperuricemia.
How Oxypurinol works
Oxypurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the blood and urine. Oxypurinol also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, resulting in further reductions of serum uric acid concentrations.
Half Life
23.3 +/- 6.0 hours
Innovators Monograph
You find simplified version here Oxypurinol