Penglobe

Penglobe Uses, Dosage, Side Effects, Food Interaction and all others data.

Penglobe is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis etc.

Penglobe is a prodrug of ampicillin and is microbiologically inactive.

Trade Name Penglobe
Availability Discontinued
Generic Bacampicillin
Bacampicillin Other Names Bacampicilina, Bacampicillin, Bacampicilline, Bacampicillinum
Related Drugs amoxicillin, doxycycline, ciprofloxacin, cephalexin, metronidazole, azithromycin, clindamycin, ceftriaxone, levofloxacin, Augmentin
Weight 400mg, 200mg,
Type Tablet
Formula C21H27N3O7S
Weight Average: 465.52
Monoisotopic: 465.156970923
Groups Approved, Investigational
Therapeutic Class
Manufacturer Astrazeneca Pharma India Ltd
Available Country India,
Last Updated: September 19, 2023 at 7:00 am
Penglobe
Penglobe

Uses

Penglobe is an ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.

For infections at the following sites: upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis, when due to sensitive strains of the following organisms: Gram-positive: streptococci (including S. faecalis and S. pneumoniae) and nonpenicillinase-producing staphylococci; Gram-negative: H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis, Salmonellae and Shigellae.

Penglobe is also used to associated treatment for these conditions: Genital infection, Infections, Intestinal, Lower Respiratory Tract Infection (LRTI), Oral Infection, Pneumonia, Skin and Subcutaneous Tissue Bacterial Infections, Upper Respiratory Tract Infection, Urinary Tract Infection, Susceptible Bacterial Infections

How Penglobe works

During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides.

Food Interaction

  • Take separate from antacids. Elevated gastric pH may reduce the bioavailability of bacampicillin.
  • Take with or without food. Food may reduce the bioavailability of bacampicillin.

Elimination Route

Absorbed following oral administration.

Innovators Monograph

You find simplified version here Penglobe

*** Taking medicines without doctor's advice can cause long-term problems.
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