Penticort

Penticort Uses, Dosage, Side Effects, Food Interaction and all others data.

Penticort is a corticosteroid.

Penticort is a topical corticosteroid. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents. Penticort reduces or inhibits the actions of chemicals in the body that cause inflammation, redness, and swelling. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man. When in an ointment form, amcinonide also helps the skin maintain moisture.

Trade Name Penticort
Availability Prescription only
Generic Amcinonide
Amcinonide Other Names Amcinónida, Amcinonide, Amcinonidum, Triamcinolonacetatcyclopentanonid
Related Drugs Humira, Cosentyx, Dupixent, prednisone, methotrexate, Remicade, Stelara, cyclosporine, infliximab, Temovate
Type
Formula C28H35FO7
Weight Average: 502.5717
Monoisotopic: 502.236681679
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Penticort
Penticort

Uses

Penticort is a topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.

For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Penticort is also used to associated treatment for these conditions: Inflammation, Pruritus

How Penticort works

The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Penticort has affinity for the glucocorticoid receptor. It has weak affinity for the progesterone receptor, and virtually no affinity for the mineralocorticoid, estrogen, or androgen receptors.

Toxicity

Results from acute toxicity studies do not indicate that any risk of acute intoxication is to be expected following a single dermal application of an overdose (application over a large area under conditions favorable to absorption) or inadvertent oral ingestion.

Food Interaction

No interactions found.

Elimination Route

Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption.

Elimination Route

Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.

Innovators Monograph

You find simplified version here Penticort

*** Taking medicines without doctor's advice can cause long-term problems.
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