Pondocillin

Pondocillin Uses, Dosage, Side Effects, Food Interaction and all others data.

Pivalate ester analog of ampicillin.

Pondocillin is the pivaloyloxymethyl ester of (the semi-synthetic penicillin) ampicillin. It is an inactive pro-drug, which is converted during its absorption from the gastrointestinal tract to the microbiologically active ampicillin, together with formaldehyde and pivalic acid, by non-specific esterases present in most body tissues. Amounts in excess of 99% of the pivampicillin absorbed are converted to ampicillin within 15 minutes of absorption.

Pondocillin
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Pondocillin
Generic	Pivampicillin
Pivampicillin Other Names	Ampicillin pivaloyloxymethyl ester, Pivaloylampicillin, Pivaloyloxymethyl ampicillinate, Pivampicilina, Pivampicillin, Pivampicilline, Pivampicillinum
Type
Formula	C₂₂H₂₉N₃O₆S
Weight	Average: 463.547 Monoisotopic: 463.177706365
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Pondocillin is an ampicillin prodrug used to treat a variety of infections.

or the treatment of respiratory tract infections (including acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia); ear, nose and throat infections; gynecological infections; urinary tract infections (including acute uncomplicated gonococcal urethritis) when caused by non penicillinase-producing susceptible strains of the following organisms: gram-positive organisms, e.g., streptococci, pneumococci and staphylococci; gram-negative organisms, e.g., H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis.

Pondocillin is also used to associated treatment for these conditions: Susceptible Bacterial Infections