Spermine
Spermine Uses, Dosage, Side Effects, Food Interaction and all others data.
Spermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values. Found in various tissues and organisms, it often acts as an essential growth factor in some bacterial species. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Spermine is a polyamine. It is an organic molecule that is involved in cellular metabolism.
Trade Name | Spermine |
Generic | Spermine |
Spermine Other Names | Musculamine, Spermina, Spermine |
Type | |
Formula | C10H26N4 |
Weight | Average: 202.3402 Monoisotopic: 202.215746852 |
Groups | Experimental, Nutraceutical |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For nutritional supplementation, also for treating dietary shortage or imbalance
How Spermine works
Spermine is derived from spermidine by spermine synthase. Spermine is a polyamine, a small organic cations that is absolutely required for eukaryotic cell growth. Spermine, is normally found in millimolar concentrations in the nucleus. Spermine functions directly as a free radical scavenger, and forms a variety of adducts that prevent oxidative damage to DNA. Oxidative damage to DNA by reactive oxygen species is a continual problem that cells must guard against to survive. Hence, spermine is a major natural intracellular compound capable of protecting DNA from free radical attack. Spermine is also implicated in the regulation of gene expression, the stabilization of chromatin, and the prevention of endonuclease-mediated DNA fragmentation.
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