Troxacitabine Uses, Dosage, Side Effects and more
Troxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
Troxacitabine is a beta-L-nucleoside analog, which has shown preclinical antitumor activity in human xenograft tumor models and antileukemic response in patients with relapsed myeloid leukemia.
| Attribute | Details |
|---|---|
| Trade Name | Troxacitabine |
| Generic | Troxacitabine |
| Troxacitabine Other Names | Troxacitabina, Troxacitabine, Troxacitabinum |
| Type | |
| Formula | C8H11N3O4 |
| Weight | Average: 213.1906 Monoisotopic: 213.074955855 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in leukemia (myeloid).
How Troxacitabine works
Troxacitabine is activated by cellular kinases and incorporated into DNA, inhibiting its replication. In contrast to other cytosine nucleoside analogs, troxacitabine is resistant to inactivation by cytidine deaminase (CD).
