Vatalinib

Vatalinib Uses, Dosage, Side Effects, Food Interaction and all others data.

Vatalinib (PTK787/ZK-222584) is a new oral antiangiogenic molecule that inhibits all known vascular endothelial growth factor receptors. Vatalinib is under investigation for the treatment of solid tumors.

Vatalinib is a novel oral angiogenesis inhibitor being developed by Schering (in collaboration with Novartis AG). Vatalinib selectively inhibits the tyrosine kinase domains of vascular endothelial growth factor (VEGF) receptors, platelet-derived growth factor (PDGF) receptor, and c-KIT.

Trade Name Vatalinib
Generic Vatalanib
Vatalanib Other Names Vatalanib, Vatalinib
Type
Formula C20H15ClN4
Weight Average: 346.813
Monoisotopic: 346.098524207
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Vatalinib
Vatalinib

Uses

Used in combination with first- and second-line chemotherapy for the treatment of metastatic colorectal cancer and non-small cell lung cancer (NSCLC).

How Vatalinib works

Vatalinib potently inhibits vascular endothelial growth factor (VEGF) receptor tyrosine kinases, important enzymes in the formation of new blood vessels that contribute to tumor growth and metastasis.

Elimination Route

Rapid onset of absorption

Half Life

Approximately 6 hours.

Innovators Monograph

You find simplified version here Vatalinib

*** Taking medicines without doctor's advice can cause long-term problems.
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