Vinacetin A

Vinacetin A Uses, Dosage, Side Effects, Food Interaction and all others data.

Vinacetin A is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Vinacetin A was derived from the actinomycete Streptomyces puniceus.

Table Of contents

• Vinacetin A
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Vinacetin A
Generic	Viomycin
Viomycin Other Names	Vinacetin A, Viomicina, Viomycin, Viomycine, Viomycinum
Type
Formula	C25H43N13O10
Weight	Average: 685.69 Monoisotopic: 685.325584661
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Vinacetin A is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.

How Vinacetin A works

Vinacetin A binds to a site on the ribosome which lies at the interface between helix 44 of the small ribosomal subunit and helix 69 of the large ribosomal subunit. The structures of this complexes suggest that the viomycin inhibits translocation by stabilizing the tRNA in the A site in the pretranslocation state. This inhibits protein synthesis.

Innovators Monograph

You find simplified version here Vinacetin A