Hyazyme

Hyazyme Uses, Dosage, Side Effects, Food Interaction and all others data.

Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.

Hyaluronidase hydrolyzes hyaluronic acid and increase diffusion of injected drugs, thus facilitating their absorption. Hyaluronidase is used for enhancing absorption and distribution of other injected drugs.

Table Of contents

• Hyazyme
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Hyazyme
Generic	Hyaluronidase (ovine)
Hyaluronidase (ovine) Other Names	Hyaluronidase (glycoprotein, sheep testis isoenzyme), Hyaluronidase (ovine), Hyaluronidase (sheep testis isoenzyme), Hyaluronidase, ovine, Ovine hyaluronidase
Type
Formula	C2455H3775N617O704S21
Weight	53870.9 Da
Groups	Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Hyazyme is a purified form of sheep hyaluronidase enzyme used as an adjunct in subcutaneous rehydration therapy and to increase absorption of other drugs and radiopaque imaging agents.

For increase of absorption and distribution of other injected drugs and for rehydration.

Hyazyme is also used to associated treatment for these conditions: Chronic Lymphocytic Leukaemia (CLL), Diffuse Large B-Cell Lymphoma (DLBCL), Follicular Lymphoma (FL), Refractory Follicular Lymphoma, Relapsed Follicular Lymphoma, Non-progressive Follicular Lymphoma, Stable Follicular Lymphoma, Parenteral rehydration therapy, Improving resorption of radiopaque agents, To increase percutaneous drug absorption

How Hyazyme works

Hyaluronidase is a spreading or diffusing substance. It increase the permeability of connective tissue through the hydrolysis of hyaluronic acid. Hyaluronidase hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This temporarily decreases the viscosity of the cellular cement and increases diffusion of injected fluids or of localized transudates or exudates, thus facilitating their absorption.

Food Interaction

No interactions found.

Innovators Monograph

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