Ketas
Ketas Uses, Dosage, Side Effects, Food Interaction and all others data.
Ketas is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume shrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). Ketas is currently in development in the U.S. (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan.
| Trade Name | Ketas |
| Generic | Ibudilast |
| Ibudilast Other Names | Ibudilast, Ibudilastum |
| Type | |
| Formula | C14H18N2O |
| Weight | Average: 230.3055 Monoisotopic: 230.141913208 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
How Ketas works
Ketas has mechanisms that include anti-inflammatory effects, such as phosphodiesterase inhibition, and neuroprotective effects, such as inhibition of nitric oxide synthesis and reduction in reactive oxygen species.
Toxicity
Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia
Half Life
19 hours
Innovators Monograph
You find simplified version here Ketas
