Sitamaquine

Sitamaquine Uses, Dosage, Side Effects, Food Interaction and all others data.

Sitamaquine (WR-6026) is an orally active 8-aminoquinoline analog in development by the Walter Reed Army Institute, in collaboration with GlaxoSmithKline (formerly SmithKline Beecham), for the potential treatment of visceral leishmaniasis.

Trade Name Sitamaquine
Generic Sitamaquine
Sitamaquine Other Names Sitamaquine
Type
Formula C21H33N3O
Weight Average: 343.5062
Monoisotopic: 343.262362693
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Sitamaquine
Sitamaquine

Uses

Investigated for use/treatment in infectious and parasitic disease (unspecified).

How Sitamaquine works

The mechanism of plasmodicidal action of sitamaquine is not completely understood. Like other quinoline derivatives, it is thought to inhibit heme polymerase activity. This results in accumulation of free heme, which is toxic to the parasites.

Innovators Monograph

You find simplified version here Sitamaquine

*** Taking medicines without doctor's advice can cause long-term problems.
Share