Tariquidar
Tariquidar Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | Tariquidar |
Generic | Tariquidar |
Tariquidar Other Names | Tariquidar |
Type | |
Formula | C38H38N4O6 |
Weight | Average: 646.744 Monoisotopic: 646.27913496 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in ovarian cancer, lung cancer, and breast cancer.
How Tariquidar works
Tariquidar is an anthranilic acid derivative third generation P-glycoprotein (P-gp) inhibitors. P-gp is a transport protein found in normal cells that has many trasport and modulatory functions, from affecting the distribution and bioavailability of drugs to mediating the migration of dendritic cells. P-gp is responsible for multidrug resistance through transport of anti-cancer drugs out of their target cells. It is proposed that tariquidar's and its derivatives may bind to the H-binding site of P-gp through multiple mechanisms of binding.
Innovators Monograph
You find simplified version here Tariquidar