Vivagel
Vivagel Uses, Dosage, Side Effects, Food Interaction and all others data.
Vivagel has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
Trade Name | Vivagel |
Generic | Astodrimer |
Astodrimer Other Names | Astodrimer, Vivagel |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
How Vivagel works
Dendrimers such as astodrimer are polymers that contain a central core, interior branches, and terminal surface groups adapted to specific targets. Vivagel has a polyanionic outer surface that provides for multiple target interactions. The active surface groups bind to gp120 proteins on HIV's surface, preventing CD4 receptor binding by healthy cells and thus blocking transmission of HIV to healthy cells.
Innovators Monograph
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