Cenisertib

Cenisertib Uses, Dosage, Side Effects, Food Interaction and all others data.

Cenisertib is an aurora kinase inhibitor.

Trade Name Cenisertib
Generic Cenisertib
Cenisertib Other Names Cenisertib
Type
Formula C24H30FN7O
Weight Average: 451.55
Monoisotopic: 451.249586777
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Cenisertib
Cenisertib

Uses

Investigated for use/treatment in solid tumors, leukemia (myeloid), myelodysplastic syndrome, and cancer/tumors (unspecified).

How Cenisertib works

R763 is a highly potent and specific inhibitor of Aurora kinase, which has been shown to block proliferation and trigger apoptosis (cell death) in several tumor cell lines including cervical, colon, lung, pancreas and prostate. The over-expression of Aurora kinase can cause cells to rapidly develop an abnormal number of chromosomes. Elevated levels of Aurora kinase are frequently associated with various human cancers and inhibition of this enzyme disrupts cell division and promotes apoptosis. [Rigel Pharmaceuticals Press Release] A probable target for R763 is Aurora kinase A (serine/threonine protein kinase 6).

Innovators Monograph

You find simplified version here Cenisertib

*** Taking medicines without doctor's advice can cause long-term problems.
Share