D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A)
D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) |
Generic | Trabedersen |
Trabedersen Other Names | DNA, D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer.
How D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) works
AP 12009 is an antisense oligodeoxynucleotide that specifically inhibits TGF-beta2. TGF-beta overexpression is a hallmark of various malignant tumors. This is due to the pivotal role of TGF-beta as it regulates key mechanisms of tumor development, namely immunosuppression, metastasis, angiogenesis, and proliferation.
Innovators Monograph
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