D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) Uses, Dosage, Side Effects and more
| Attribute | Details |
|---|---|
| Trade Name | D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) |
| Generic | Trabedersen |
| Trabedersen Other Names | DNA, D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer.
How D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) works
AP 12009 is an antisense oligodeoxynucleotide that specifically inhibits TGF-beta2. TGF-beta overexpression is a hallmark of various malignant tumors. This is due to the pivotal role of TGF-beta as it regulates key mechanisms of tumor development, namely immunosuppression, metastasis, angiogenesis, and proliferation.
