Trabedersen Uses, Dosage, Side Effects and more
Attribute | Details |
---|---|
Trade Name | Trabedersen |
Generic | Trabedersen |
Trabedersen Other Names | DNA, D(P-THIO)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A) |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in brain cancer, colorectal cancer, melanoma, and pancreatic cancer.
How Trabedersen works
AP 12009 is an antisense oligodeoxynucleotide that specifically inhibits TGF-beta2. TGF-beta overexpression is a hallmark of various malignant tumors. This is due to the pivotal role of TGF-beta as it regulates key mechanisms of tumor development, namely immunosuppression, metastasis, angiogenesis, and proliferation.