Pagoclone
Pagoclone Uses, Dosage, Side Effects, Food Interaction and all others data.
Pagoclone is an anxiolytic drug from the cyclopyrrolone family, which is related to other more well known drugs such as the sleeping medication zopiclone. It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures.
Pagoclone was originally developed as an anti-anxiety drug, but never commercialised. It is a partial agonist acting at GABAA receptors in the brain. In contrast to zopiclone, pagoclone produces anxiolytic effects with little or no sedative or amnestic actions at low doses.
| Trade Name | Pagoclone |
| Generic | Pagoclone |
| Pagoclone Other Names | Pagoclone |
| Type | |
| Formula | C23H22ClN3O2 |
| Weight | Average: 407.893 Monoisotopic: 407.14005467 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the potential treatment of panic and anxiety disorders.
How Pagoclone works
Pagoclone is a subtype-selective drug which binds primarily to the alpha2/alpha3 subtypes of the GABAA receptor which are responsible for the anti-anxiety effects of these kind of drugs, but has relatively little efficacy at the alpha1 subtype which produces the sedative and memory loss effects.
Innovators Monograph
You find simplified version here Pagoclone
